Condition 1: Sexual dysfunction. Condition 2: Depression. Sexual dysfunction not due to a substance or known physiological condition Other depressive episodes
Conditions
Interventions
Intervention 1: Intervention group 1 (women with vitamin D deficiency): Oral capsules of vitamin D3 4000 IU/d (one 4000 IU or two 2000 IU capsules) for 3 months, prepared by Dana pharmaceutical compan
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Married women aged 18-40 years Educational level at minimum 6 years and ability to complete study questionnaires The serum level of 25-hydroxy vitamin D less than 20 ng/ml in the vitamin D deficiency group and 20-30 ng/ml in the vitamin D insufficiency group Impaired sexual function (a score of 28 or less based in the FSFI) Living with her husband in the last month and following three months
Exclusion criteria
Exclusion criteria: Unwillingness to participate in the study Pregnancy The first six months after delivery Severe depression based on Beck Depression Inventory Consumption of more than 50 000 IU vitamin D supplements during the past 3 months Drug and alcohol addiction of each of the couples Occurrence of any stressful event or important psychological problem in the last 6 months, according to participant report Taking any drug affecting serum levels of vitamin D (e.g. glucocorticoids, glycosides, thiazide diuretics, phenobarbital, phenytoin, cholestyramine, and calcium-vitamin D supplements) History of chronic diseases such as thyroid and pituitary diseases, according to participant report History of any cancer History of infertility Taking antidepressants or antipsychotics in the past 6 months Genital surgery Vaginal infection, according to participant report Premature menopause Husband major sexual function problems, according to woman report
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sexual function score. Timepoint: At the baseline (before intervention) and just after completion of the intervention (3 months after initiation of the intervention ). Method of measurement: Using the FSFI questionnaire.;Depression score. Timepoint: At the baseline (before intervention) and just after completion of the intervention (3 months after initiation of the intervention ). Method of measurement: Using the Beck Depression Inventory questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side events. Timepoint: during 12 weeks after initiation of intervention. Method of measurement: self- report.;Level of serum vitamin D. Timepoint: At the baseline (before intervention) and just after completion of the intervention (3 months after initiation of intervention ). Method of measurement: Measurement of serum vitamin D levels by kits using enzyme immunoassay.;Satisfaction from the intervention. Timepoint: At the end of the intervention. Method of measurement: Using 10 cm visual analogue scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactParishan Bahramy
Tabriz University of Medical Sciences
Outcome results
None listed