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Effects of systemic melatonin and non surgical periodontal therapy on serum ferritin inpatients with periodontitis disease

Effects of systemic melatonin and non surgical periodontal therapy on serum ferritin inpatients with periodontitis disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20100412003690N9
Enrollment
42
Registered
2018-12-08
Start date
2018-11-26
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis. Chronic periodontitis

Interventions

Intervention 1: Intervention group:The Vi-One chlorohexidine 2%mouthwash will be used for one minute to wash teeth in the morning and at night, and oral melatonin tablets will be taken for a period of

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Lake of loss the joints in interdental areas larger than 4 mm. 2.Absent depth of the envelope larger than 4 mm in the interdental areas. 3. The bleeding tendency is less or equal to 10% in total. 4. Age older than twenty years

Exclusion criteria

Exclusion criteria: 1. People with systemic disorders, such as epilepsy, schizophrenia, chronic infections, neoplastic disease, or any disease that affects the immune system. 2.Invader Periodontium 3. Smokers and Alcoholics 4. Pregnancy or breastfeeding 5. Patients taking medications that can affect the level of melatonin 6. Those who have had periodontal treatment in the last 6 months. 7.People working in night shifts. 8.Under-20years. 9.People with mental disabilities

Design outcomes

Primary

MeasureTime frame
Serum ferritin level. Timepoint: Before the start, One and three months later. Method of measurement: Blood sampling.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoomeh Faramarzie

Tabriz University of Medical Sciences

faramarzim@tbzmed.ac.ir+98 41 3335 5965

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026