Periodontitis. Chronic periodontitis
Conditions
Interventions
Intervention 1: Intervention group:Aloe vera gel will be injected into the periodontal envelope using an insulin syringe so that the gel enters and fills up to the apical envelope and the gel exits th
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 50 Years
Inclusion criteria
Inclusion criteria: Moderate to severe ?chronic periodontitis Age 35-50 Have at least 4 teeth with probe depth of 4 mm or more in each jaw quadrant Consent to participate in the study Patients candidate for non-surgical treatment
Exclusion criteria
Exclusion criteria: Allergy to aloe vera or its products Use of tobacco Endodontic and periodontal compound lesions Periapical lesions Pregnancy Severe dental caries Semi-impacted teeth Orthodontic patients Systemic diseases and systemic or topical antibiotic users 6 Months befor study Patients with periodontal disease during the past 6 months and patients receiving periodontal treatment 6 months before study Patients receiving NSAIDs one month before sampling
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plaque Index (PI). Timepoint: Before entrance in the study and 30 days after initial treatment. Method of measurement: Using the index (O'Leary 1972).;Gingival Index (GI). Timepoint: Before entrance in the study and 30 days after initial treatment. Method of measurement: According to the Loe & Sillness Index.;Probe depth (PD). Timepoint: Before entrance in the study and 30 days after initial treatment. Method of measurement: Using Williams probe 6 levels of teeth.;IL-1B. Timepoint: Before entrance in the study and 30 days after initial treatment. Method of measurement: Using ELISA kit.;IL-17. Timepoint: Before entrance in the study and 30 days after initial treatment. Method of measurement: Using ELISA kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMasoomeh Faramarzi
Tabriz University of Medical Sciences
Outcome results
None listed