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Evaluation of the effect of silymarin on volume Expression Milk of mothers with Preterm Infant

Evaluation of the effect of silymarin on volume Expression Milk of mothers with Preterm Infant in the Neonatal Intensive Care Unit

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20100411003679N4
Enrollment
30
Registered
2023-08-28
Start date
2023-07-11
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Volume of breast milk.

Interventions

Intervention 1: Intervention group: Mothers in the experimental group are given Silimarin tablets in the form of liver-coated tablets of 140 mg three times a day. Intervention 2: Control group: The pl

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: inclusion criteria for mothers: presence of the mother in the neonatal intensive care unit, having decided to breastfeed. inclusion criteria for infants: premature infants with a gestational age of more than 28 weeks, a calendar age of at least three days.

Exclusion criteria

Exclusion criteria: Exclusion criteria for mothers: mother's addiction, suffering from tuberculosis, AIDS, cancer, presence of breast abscess, presence of purulent secretions in breast milk or presence of blood in breast milk, mood disorders such as depression or psychosis after childbirth. Exclusion criteria for babies: having defects Clear genetic and congenital or disorders of the digestive system that prevent breastfeeding, such as gastroschisis, emphalocele, cerebral hemorrhage with degree 3 and 4, a baby undergoing surgery or mechanical ventilation.

Design outcomes

Primary

MeasureTime frame
Volume of breast milk. Timepoint: Average milk expressed by mothers on the first, 7th and 14th days of the intervention. Method of measurement: The amount of expressed milk is measured with a 20 cc syringe and recorded with the time in the checklist during the two weeks of the intervention.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKhadijeh Dehghani

Yazd University of Medical Sciences

dehghanish@ssu.ac.ir+98 35 3724 0171

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026