Prediabetes. Abnormal glucose tolerance test
Conditions
Interventions
Intervention 1: Intervention group: 50000 units once every two weeks vitamin D of Zahravi company for 3 month. Intervention 2: Control group: Intake a Placebo perl containing sunflower oil, which is s
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Willingness to cooperate Women aged 18 to 65 years with prediabetes Body mass index in the range of 30-40 Kg/m2
Exclusion criteria
Exclusion criteria: Serum Vitamin D Levels higher than 100 µg / L Smoking and alcohol Pregnancy and lactation Intake of various drugs, including drugs affecting blood sugar and lipid levels Intake of drugs or dietary supplements affecting the body weight Surgery in last three months Having chronic neurological diseases, diabetes, cardiovascular, liver, kidney, Cushing's syndrome, rheumatoid arthritis, cancer and other diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycemic indices. Timepoint: Baseline and 12 weeks after the intervention. Method of measurement: Glycemic indexes (from indicators of metabolic status) including fasting blood sugar by enzymatic method, insulin by ELISA and insulin resistance by formula, will be measured or calculated.;Lipid profile. Timepoint: Baseline and 12 weeks after the intervention. Method of measurement: Lipid profile ( from indicators of metabolic status) including total cholesterol, triglycerides and high-density lipoprotein will be measured enzymatically, and low-density lipoprotein will be calculated using the friedwald formula.;Omentin. Timepoint: Baseline and 12 weeks after the intervention. Method of measurement: ELISA.;Serum Vitamin D. Timepoint: Baseline and 12 weeks after the intervention. Method of measurement: ELISA. | — |
Secondary
| Measure | Time frame |
|---|---|
| Obesity indices. Timepoint: Baseline and 12 weeks after the intervention. Method of measurement: Obesity indices including weight with scales and waist circumference and hip circumference will be measured with a tape measure. Body mass index will be calculated with the formula.;Body composition. Timepoint: Baseline and 12 weeks after the intervention. Method of measurement: Body composition will be measured by Bio impedance (BIA) method usingTanita body composition analyzer.;Dietary intake. Timepoint: Baseline and 12 weeks after the intervention. Method of measurement: The food record questionnaire will be used to assess food intake including energy, carbohydrate, protein and fat. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRoghayeh Molani-Gol
Tabriz University of Medical Sciences
Outcome results
None listed