Type 2 diabetes with microalbuminuria. Type 2 diabetes mellitus with renal complications
Conditions
Interventions
Intervention 1: Intervention group: Pine bark extract (Oligopin) will be taken as two capsules of 50 mg with a meal (breakfast and lunch) for 8 weeks, the product of Aramis Faramad Company. Interventi
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: Volunteered to participate in the study with type 2 diabetes People (men and women) who have been diagnosed with diabetes for at least one year. Age:Women 30-50 years old Men: 30-65 years old Microalbuminuria diagnosis based on ACR criteria in randomized urine specimen
Exclusion criteria
Exclusion criteria: history of congestive heart failure,Infectious diseases of the urine, prostate,Acute febrile illnessUncontrolled blood pressureGlomerulonephritisPolycystic kidney disease,Acute hyperglycemia,The field of hereditary nephropathy Insulin therapy smoking Extreme sports activity (24 hours before sample collection) Pregnancy-lactation Use of any type of multi-vitamin supplement and so on during the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood sugar. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With Spectrophotometer.;Level of Serum Insulin. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With ELISA.;Homeostatic Model Assessment of Insulin Resistance(HOMA-IR). Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Calculated According to The Formula.;HbA1C. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With HPLC.;Total Cholestrol. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With Spectrophotometer.;HDL-C. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With Spectrophotometer.;LDL-C. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Calculated According to The Friedwald Formula.;TG. Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With Spectrophotomete.;ICAM-1(Intra cellular adhesion molecule1). Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With ELISA.;VCAM-1( vascular cell adhesion molecule 1 ). Timepoint: Before of Intervention and 8 Weeks After Intervention. Method of measurement: Blood Sampling and Analysing With ELISA. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactElham navval esfahlan
Tabriz University of Medical Sciences
Outcome results
None listed