polycystic ovary syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention 1: Intervention group: En Interventions 1: 500mg capsules of synbiotic 1 per day for 8 weeks Interventions ,, Half an hour after lunch, the product of Biostimiran Company. Intervention 2:
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 44 Years
Inclusion criteria
Inclusion criteria: • Women with PCOS aged 20-40 years • Diagnosis of PCOS in patients by Gynecologist and according to Rotterdam Standard 2003• The BMI range is between 40-25 m ^ 2/ kg
Exclusion criteria
Exclusion criteria: • History of thyroid disorders, hyperprolactinemia, Cushing's syndrome, liver and kidney disease, cardiovascular disease, digestive diseases (food allergies, celiac disease, irritable bowel disease), high blood pressure and diabetes. Diagnosis of non-disease By asking the patient, using the existing tests and under the supervision of the doctor will be done. • Pregnancy and breastfeeding • Consumers of anti-obesity drugs and blood lipid lowering drugs, anticoagulants and glucocorticoids • Using a weight loss diet • smoking • Athlete or regular exercise • Sensitivity to synbiotic and probiotic capsules • Antibiotic use a month ago • Use of any dietary supplements in the last 2 months or during the study • Receiving probiotics, perebiotic, synbiotics during the last three months and during the study • Regular consumption of probiotic products
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood sugar. Timepoint: Begining and end of the intervention. Method of measurement: Analysing With Spectrophotometer.;Level of Serum Insulin. Timepoint: Begining and end of the intervention. Method of measurement: Analysing with ELISA.;HOMA-IR. Timepoint: Begining and end of the intervention. Method of measurement: Calculated According to The Formula.;Total Cholestrol. Timepoint: Begining and end of the intervention. Method of measurement: Analysing With Spectrophotometer.;HDL-C. Timepoint: Begining and end of the intervention. Method of measurement: Analysing With Spectrophotometer.;LDL-C. Timepoint: Begining and end of the intervention. Method of measurement: Calculated According to The Friedewald Formula.;TG. Timepoint: Begining and end of the intervention. Method of measurement: Analysing With Spectrophotometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Apelin. Timepoint: Beginning and end of intervention. Method of measurement: Analysing With ELISA.;Anthropometric indexes. Timepoint: Beginning and end of intervention. Method of measurement: Measuring with scales and meters. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSima Darvishi
Tabriz University of Medical Sciences
Outcome results
None listed