Fetal distress in pregnancy.
Conditions
Interventions
Intervention 1: Intervention group: a group of 104 people who received a package containing three oral capsules of sildenafil 50 mg brand Marham Darou (SDF), prepared by the pharmacy, up to a maximum
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Age between 18-40 years Single pregnancy Term pregnancy (37-41 weeks) Normal fetal structure and without any anomalies Cephalic presentation Estimated weight above 2500 grams Without CPD Candidate for normal vaginal delivery
Exclusion criteria
Exclusion criteria: Drug reaction to Sildenafil Fetal anomalies Metabolic disorder Cardiac disorders Renal disorders Visual disorders Liver anomalies Previous cesarean Preeclampsia HTN Alcohol Taking medications Nitrate a-blocker
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Need for cesarean section. Timepoint: The first dose of sildenafil or placebo when the participant is in the active phase of labor. For delivery, she enters the labor department and is given. Sildenafil is given orally 50 mg every 8 hours for a maximum of 3 doses. Method of measurement: The patient's blood pressure is measured every 15-30 minutes. Fetal heart rate is monitored. | — |
Secondary
| Measure | Time frame |
|---|---|
| Type of delivery. Timepoint: Until every stage of childbirth. Method of measurement: Will be recorded in the checklist.;Cesarean section indication. Timepoint: Until every stage of childbirth. Method of measurement: Will be recorded in the checklist.;Labor duration. Timepoint: Until every stage of childbirth. Method of measurement: Will be recorded in the checklist.;Abnormal bleeding during and after delivery. Timepoint: Until after delivery. Method of measurement: Will be recorded in the checklist.;Meconium excretion. Timepoint: Until every stage of childbirth. Method of measurement: Will be recorded in the checklist.;Need for fetal blood sampling. Timepoint: Until every stage of childbirth. Method of measurement: Will be recorded in the checklist.;Fetal distress. Timepoint: Until every stage of childbirth. Method of measurement: Will be recorded in the checklist.;Birth weight. Timepoint: After delivery. Method of measurement: Will be recorded in the checklist.;Neonatal sex. Timepoint: After delivery. Method of measurement: Will be recorded in the checklist.;Apgar scores. Timepoint: After delivery. Method of measurement: Will be recorded in the checklist.;Umbilical artery pH. Timepoint: Until every stage of childbirth. Method of measurement: Will be recorded in the checklist.;Need for neonatal resuscitation. Timepoint: After delivery. Method of measurement: Will be recorded in the checklist.;Length of time in neonatal intensive care unit. Timepoint: After delivery. Method of measurement: Will be recorded in the checklist.;Seizures. Timepoint: After delivery. Method of measurement: Will be recorded in the checklist.;Neonatal encephalopathy. Timepoint: After delivery. Method of measurement: Will be recorded in the checklist.;Fetal and infant death. Timepoint: After delivery. Method of measurement: Will be recorded in the checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzadeh mahmoudi eisa abadi
Rasht University of Medical Sciences
Outcome results
None listed