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The effect of ear acupressure on endocrine therapy-associated musculoskeletal pain in breast cancer survivors

The effect of ear acupressure on endocrine therapy-associated musculoskeletal pain in breast cancer survivors

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20100211003329N13
Enrollment
52
Registered
2025-10-27
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer. Malignant neoplasm of breast

Interventions

Intervention 1: Intervention group: , the researcher will attach ZHONG YANG brand of Vakaria seeds made in China to the points used to relieve stress and pain (including Shenmen, Sympathetic, Subcorte

Sponsors

Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Diagnosis of stage 1 to 3 hormone-dependent breast cancer (histology report), without recurrence and metastasis to distant sites Taking tamoxifen or aromatase inhibitor drugs for at least 3 months The type of medication must be stable for at least 2 months before the start of the study. Development or worsening of musculoskeletal pain following initiation of endocrine therapy Experiencing musculoskeletal pain for at least 2 months and at least 15 days per month Having pain with an intensity of at least 3 on a scale of 0 to 10 (sensory dimension of the Persian version of the Short Pain Questionnaire) in the week before the start of the study Iranian nationality, resident of Kashan and its suburbs Postmenopausal (age 60 years or older, history of oophorectomy, history of hysterectomy, or amenorrhea for at least 12 months) At least 4 weeks have passed since the completion of surgical, chemotherapy, and radiotherapy treatments. Organ health in the earlobe area

Exclusion criteria

Exclusion criteria: Any type of surgery, musculoskeletal disease, orthopedic or neurological problems during the study Performing any type of intense physical activity or starting a sports activity during the study Use of corticosteroids or opioids during the study Allergy to glue Hospitalization due to physical or mental problems during the study Performing physiotherapy during the study Taking nutritional supplements during the study (except calcium and vitamin D) Changes in endocrine treatment plan during the study Combined use of other complementary therapies Withdrawal from further cooperation during the study Failure to meet the criteria regarding the average daily pressure applied to the heads during each week of intervention (less than 6 minutes per day) Experiencing serious stress, lack of access, death engaging in professional sports activities having fibromyalgia, arthritis and inflammatory arthritis requiring medication, active cancer, rheumatoid arthritis, peripheral nerve problems in the limbs, cognitive impairment, and lymphedema based on patient records and self-report. use of narcotics and corticosteroids using acupuncture in the past 6 months amputation, fracture, or bone surgery within the past 6 months

Design outcomes

Primary

MeasureTime frame
Musculoskeletal pain score. Timepoint: At the beginning of the study, after the end of the intervention, and 4 weeks after the end of the intervention. Method of measurement: Persian version of the Brief Pain Questionnaire.

Secondary

MeasureTime frame
Pain interference score. Timepoint: weekely. Method of measurement: Report of patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Tagharrobi

Kashan University of Medical Sciences

tagharrobi_z@yahoo.com+98 31 5510 3119

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026