Chlamydial Cervicitis. Chlamydial infection of genitourinary tract, unspecified
Conditions
Interventions
Intervention 1: Control group: Oral Azithromycin and syndromic diagnostic method. Azithromycin 1 g oral single dose (two 500mg) . Azithromycin can be taken with food, after or before meals. This is D
Real-Time PCR. Azithromycin 1 g oral single dose (two 500mg) and Moxifloxacin tablets 400 mg daily for 7 days. On the first day of treatment, oral azithromycin 1000 mg is administered as a single do
Real-Time PCR. Azithromycin 1 g oral single dose (two 500mg). Ethiologic Diagnostic Method Real-Time PCR : A liquid-based sample is used for NAAT to study chlamydia.
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Women aged 18-35 Having just one partner in the last two months Married and sexually active Clinical diagnosis of chlamydial cervicitis and confirmation of diagnosis by Real-Time PCR (in the etiological diagnostic group of PCR) Syndrome diagnosis of chlamydial cervicitis includes diagnosis based on a set of symptoms that can be found during the history and examination of the patient (in the diagnostic syndromic group)
Exclusion criteria
Exclusion criteria: Concomitant use of drugs that interfere with azithromycin or moxifluxacin Having a history of allergy to Quinolones or Macrolides Use of intrauterine device pregnancy and pregnancy intent in the next 3 months lactation participating in other studies and drug use over the past 4 weeks abnormal uterine bleeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Status of patient's complaints includes vaginal discharge, abdominal pain, painful intercourse. Timepoint: One month and three month after treatment. Method of measurement: Complaint checklist.;Status of clinical findings includes swollen and fragile cervix, and mucopurulent secretions. Timepoint: One month and three month after treatment. Method of measurement: Clinical findings check list.;Lab results. Timepoint: One month and three month after treatment. Method of measurement: Nucleic Acid Amplification Test (Polymerase Chain Reaction). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahrokh Dolatian
Shahid Beheshti University of Medical Sciences
Outcome results
None listed