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Evaluation of effects of Gabapentin, Dexamethasone and Ropivacaine on tonsillectomy pain in adults.

Evaluation of effects of Gabapentin, Dexamethasone and Ropivacaine on pain after tonsillectomy surgery in adult patients.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20100127003213N10
Enrollment
50
Registered
2023-05-14
Start date
2023-06-01
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tonsillectomy. Acute tonsillitis, unspecified

Interventions

Intervention 1: Intervention group: Patients will use 300 mg of Gabapentin orally three times a day three days before the operation, and this regimen will continue until ten days after the operation.

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Adult patients with ASA grade I or II (American Society of Anesthesiology classification) patients between 18 and 40 years old Body mass index (BMI) between 18 and 25 Candidate for tonsillectomy or adenotonsillectomy with diagnosis of tonsillitis The distance between the hospital and the patient's place of residence should be a maximum of 30 minutes by car

Exclusion criteria

Exclusion criteria: Allergy to the drugs used in the study Positive history of liver, kidney, Coagulation disorders, Diseases of the digestive system, depression and anxiety Positive history of uncontrolled diseases of the cardiovascular system Addiction to drugs Obstructive sleep apnoea Taking painkillers other than study drugs in 24 hours before surgery

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Every 15 minutes in the recovery room and three times a day (morning, noon and night) for ten days. Method of measurement: Visual Analog Scale for Pain.

Secondary

MeasureTime frame
The quality of the patient's sleep. Timepoint: Every day for ten days. Method of measurement: In respect to standardized questionnaire.;The first time to start normal food. Timepoint: Every day for ten days. Method of measurement: Patient history taking.;Patient satisfaction rate. Timepoint: Every day for ten days. Method of measurement: In respect to standardized questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Mohebpour

Shiraz University of Medical Sciences

ali_mohebpour@yahoo.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026