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Effect of synbiotics in bipolar disorder

Investigating the effectiveness of synbiotics on cognition and the quality of life of euthymic phase one bipolar patients.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20100127003210N30
Enrollment
42
Registered
2025-04-12
Start date
2025-04-20
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar.

Interventions

Intervention group: Daily reception of a capsule containing Familact made by Zist Takhmir Company for 8 weeks.

Sponsors

Faculty of pharmacy, Shahid Beheshti University of Medical Scienses
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 70 Years

Inclusion criteria

Inclusion criteria: Phase I euthymic bipolar patients aged between 15 and 70 years who gave their written consent

Exclusion criteria

Exclusion criteria: Not taking probiotic or synbiotic supplements in the same period before starting the study No history of organic brain diseases Schizophrenia Pregnancy and breastfeeding Active infection convulsions

Design outcomes

Primary

MeasureTime frame
Quality of life. Timepoint: At the beginning of the study and 60 days after starting tto consume the product containing synbiotics. Method of measurement: Quality of life enjoyment and satisfaction questionnaire.;Quality of life. Timepoint: At the beginning of the study and 60 days after starting tto consume the product containing synbiotics. Method of measurement: WHO quality of life questionnaire.

Secondary

MeasureTime frame
Cognition assessment by COBRA questionaire. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Maria Tavakoli Ardakani

Shahid Beheshti University of Medical Sciences

mariatavakoli@yahoo.com+98 21 8820 0085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026