Condition 1: Oral mucositis. Condition 2: Gastrointestinal mucositis. Oral mucositis (ulcerative) due to antineoplastic therapy Gastrointestinal mucositis (ulcerative)
Conditions
Interventions
Intervention 1: Intervention group: receiving propolis, in amounts of 7.5 ml, from the mouthwash form, every 12 hours, for 15 days and one tablet, from the oral form, every 8 hours, for 10 days, along
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: All patients hospitalized in bone marrow transplantation who received conditioning chemotherapy regimen Patient satisfaction and cooperation to participate in the study Ability to communicate and answering questions during the period of mucositis Patients from previous chemotherapy or radiotherapy should not have oral mucositis and should be included in the study from the beginning of treatment
Exclusion criteria
Exclusion criteria: History of allergies to propolis or other components of mouthwash and oral tablet History of asthma, seasonal allergies and history of aspirin allergy Taking anticoagulant drugs such as warfarin Fasting blood sugar above 150 mg/dl
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mucositis. Timepoint: First day of chemotherapy until engraftment day. Method of measurement: WHO scoring system. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fever grade. Timepoint: From the first day of chemotherapy until engraftment time. Method of measurement: Submit a fever above 38.3 °C for patients.;The need for total parenteral nutrition (TPN). Timepoint: During the study period. Method of measurement: Sign the days of parenteral nutrition intake.;The amount of narcotics analgesics needed. Timepoint: Daily. Method of measurement: Patient's medication list.;The amount of antibiotics needed. Timepoint: Daily. Method of measurement: Patient's medication list. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahsa Khanzadeh
Shahid Beheshti University of Medical Sciences
Outcome results
None listed