Effect of Vancomycin as antibiotic lock technique in prevention of catheter associated infection in stem cell transplantation patientsV

Effect of Vancomycin as antibiotic lock technique in prevention of catheter associated infection in stem cell transplantation patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20100127003210N18

Enrollment

Registered

2019-09-09

Start date

2019-11-22

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

catheter- related Blood stream infection (CRBSI). Streptococcus, Staphylococcus, and Enterococcus as the cause of diseases classified elsewhere

Interventions

Intervention 1: Intervention group (5 mg vancomycin, 2500 IU/ml heparin): Every night at a certain time, patients in the intervention group receive the block solution (vacomycin-heparin) . This block

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All of patients undergoing HSCT whom non-tunneled CVC (arrow) will be inserted newly.

Exclusion criteria

Exclusion criteria: Hypersensivity to Vancomycin

Design outcomes

Primary

Measure	Time frame
Fever, erythema, purulence (catheter exit site), swelling. Timepoint: observe for 21 days from catheterization. Method of measurement: clinical examination, thermometer.;Infection. Timepoint: observe for 21 days from catheterization. Method of measurement: Blood culture (peripheral, catheter).	—

Secondary

Measure	Time frame
WBC and Platelet engraftment. Timepoint: start of antibiotic lock until 21 days after. Method of measurement: CBC.;Hospitalization time. Timepoint: from day of antibiotic lock until hospital clearance. Method of measurement: Day count.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaria Tavakoli Ardakani

Shahid Beheshti University of Medical Sciences

mariatavakoli@sbmu.ac.ir+98 21 8820 0085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026