Levofloxacin in Hematopoetic stem cell transplant

Comparison of The Efficacy of Levofloxacin and Ciprofloxacin in Prevention of Bacterial Infection in Allogeneic Hematopoietic Stem Cell Transplant Recipients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20100127003210N17

Enrollment

Registered

2019-08-23

Start date

2019-02-20

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

antibiotic prophylaxis in hematopoetic stem cell transplantation. Complications of bone marrow transplant

Interventions

Intervention 1: Intervention group: receiving Levofloxacin by dose of 500 mg per day in form of one tablet which is taken orally or intravenously if the patient is unable to take orally from day 1 pos

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate for Allogeneic Stem Cell Transplantation Age over 18

Exclusion criteria

Exclusion criteria: Chronic renal failure Age over 65 Pregnancy Unwillingness to participate in the study

Design outcomes

Primary

Measure	Time frame
Fever detection. Timepoint: every 6 hours till engraftment. Method of measurement: Via mercury thermometer.;Infection. Timepoint: Daily till engraftment happen. Method of measurement: 1. Clinical sign and symptoms. 2.Laboratory data.	—

Secondary

Measure	Time frame
Duration of neutropenic status. Timepoint: Daily. Method of measurement: Blood Neutrophile count.;Hospital length of stay. Timepoint: Daily. Method of measurement: recording number of hospitalized days.;Need for other antibiotic consuption. Timepoint: Daily. Method of measurement: Patient's medication list.;Engraftment time. Timepoint: Daily. Method of measurement: Blood cells count.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Omid Moradi

Shahid Beheshti University of Medical Sciences

O_moradi@outlook.com+98 21 8820 0118

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026