Alzheimer Disease. Alzheimer's disease
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Having of mild type of Alzheimer's Disease Receiving one of the anticholinesterase drugs for treating Alzheimer's from three months ago aged between 60-80
Exclusion criteria
Exclusion criteria: Having any other type of Dementia Any history of using Memantine or Riluzole History of using medications with glutamatergic interaction History of alcohol and opium abuse History of diseases such as Parkinson's disease, epilepsy, stroke, high blood pressure, uncontrolled diabetes, MS, mental retardation, CNS tumors, Huntington, subdural Hematoma, history of major psychiatric diseases History of severe head trauma that results in loss of consciousness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function assessment. Timepoint: The first day and the 90th day of study. Method of measurement: Using the test of Mini Mental State Examination (MMSE).;Assessment of memory. Timepoint: The first day and the 90th day of study. Method of measurement: Using the test of Delayed recall test.;Assessment of disease progression. Timepoint: The first day and the 90th day of study. Method of measurement: Using the Functional Assessment Staging Tool (FAST). | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug side effect. Timepoint: fourth week. Method of measurement: ask from patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tehran University of Medical Sciences