Investigating the effect of essential oil of thyme on oral microbial burden in mechanical ventilated ICU patients.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20100124003146N6

Enrollment

Registered

2019-03-10

Start date

2019-01-21

Completion date

Unknown

Last updated

2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral thrush. Candidal stomatitis

Interventions

Intervention 1: intervention group1: Mouthwash group with Thyme essential oil. The mouthwash, which is made by Barij essence company is made up of 10% glycidic solution, will be used twice a day (morn

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All the patients under the mechanical ventilation in intensive care units

Exclusion criteria

Exclusion criteria: Patients with no prohibition for mouthwash Patients with no sensitivity to thyme

Design outcomes

Primary

Measure	Time frame
Oral microbial load. Timepoint: before using mouthwash and seven days after the intervention. Method of measurement: oral culture.	—

Secondary

Measure	Time frame
Anti bio-gram. Timepoint: before and seven days after intervention. Method of measurement: sample of oral culture.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Esmail Azizi-Fini

Kashan University of Medical Sciences

azizi-es@kaums.ac.ir+98 31 5554 0021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026