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The effect of synbiotics on oxidative stress indicators

The effect of synbiotic supplementation on oxidative stress indicators and nutritional status in professional futsal athletes

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20100123003140N24
Enrollment
30
Registered
2024-08-21
Start date
2024-08-16
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oxidative Stress: This condition involves an imbalance between free radicals and antioxidants, leading to cellular damage. our study investigates how synbiotic supplementation affects oxidative stress levels in futsal players.Nutritional Status: Refers to the health condition determined by diet and nutrient intake. our study examines the impact of synbiotic supplements on the nutritional status of professional futsal players..

Interventions

Intervention 1: Intervention group: Football players in this group will receive a synbiotic supplement daily (one capsule per day) for 8 weeks. Intervention 2: Control group: Participants in this grou

Sponsors

Jeeroft University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Male gender People with at least 1 year of futsal sports experience Having at least 2-3 futsal practices per week Being a permanent member of the team and registering one's profile in the national league Not having specific diseases such as autoimmune diseases, metabolic disorders, infectious and inflammatory diseases, etc. Declare agreement to participate in the plan and complete the plan's informed consent Not taking other sports supplements

Exclusion criteria

Exclusion criteria: Having a specific muscle injury or disease before the start of the study Intolerance and sensitivity to probiotics and similar products Taking antibiotics, anti-inflammatory drugs, painkillers, acute and chronic disease, drugs for acute and chronic disease or other drugs in the last month Using drugs that affect lipid metabolism, such as cholesterol-lowering drugs, estrogen, progesterone, diuretics, niacin, tricyclic antidepressants, antiepileptic drugs (phenytoin, valproic acid, carbamazepine, and phenobarbital) and taking drugs that affect appetite and body weight. , drug for controlling blood sugar in diabetic patients and insulin therapy Smoking or drinking alcohol Improper use of supplements or any non-cooperation Absence and non-attendance in competitions and training sessions

Design outcomes

Primary

MeasureTime frame
Measurement of oxidative stress levels in professional futsal players, assessed through biomarkers such as malondialdehyde (MDA) and total antioxidant capacity (TAC). Timepoint: Measurement will be conducted at baseline, and then at the end of the intervention. Method of measurement: Oxidative stress will be measured using blood samples analyzed for MDA and TAC levels via spectrophotometry.

Secondary

MeasureTime frame
Assessment of nutritional status and nutritional intake. Timepoint: Measurement will be conducted at baseline, and then at the end of the intervention. Method of measurement: Nutritional status will be assessed using 3 day dietary recall questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBahram Pourghassem Gargari

Tabriz University of Medical Sciences

pourghassemb@tbzmed.ac.ir+98 41 1435 7580

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026