Muscle damage.
Conditions
Interventions
Intervention 1: Intervention group: Femilact synbiotic product (probiotic + prebiotic) with 30 oral capsules, gluten-free, containing a mixture of probiotic strains: Lactobacillus rhamnosus, Lactobaci
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Male gender Not having specific diseases such as autoimmune diseases, metabolic disorders and infectious and inflammatory diseases People with at least 1 year of futsal sports experience Having at least 2-3 futsal practice per week Being a permanent member of the team and registering one's profile in the national league. Declare agreement to participate in the plan and complete the plan's informed consent
Exclusion criteria
Exclusion criteria: Intolerance and sensitivity to synbiotics and similar products Taking antibiotics, painkillers, acute and chronic illness, acute and chronic illness medications or other medications in the last month Using drugs that affect lipid metabolism, such as cholesterol-lowering drugs, estrogen, progesterone, diuretics, niacin, tricyclic antidepressants, antiepileptic drugs (phenytoin, valproic acid, carbamazepine, and phenobarbital) and taking drugs that affect appetite and weight. Body, medicine to control blood sugar having specific muscle injuries and diseases such as myopathies (muscular dystrophy diseases); Neuropathies (Charcot-Marie-Tooth disease), nerve and muscle junction diseases (congenital myasthenia syndrome), motor neuron diseases (spinal muscular atrophy), fibromyalgia, myasthenia gravis before starting the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum creatine kinase levels. Timepoint: Before and after the intervention. Method of measurement: Enzymatic method.;Serum lactate dehydrogenase levels. Timepoint: Before and after the intervention. Method of measurement: Enzymatic method.;Serum troponin levels. Timepoint: Before and after the intervention. Method of measurement: Enzymatic method.;Serum aspartate aminotransferase levels. Timepoint: Before and after the intervention. Method of measurement: Enzymatic method.;Serum levels of IL-6. Timepoint: Before and after the intervention. Method of measurement: ELIZA KIT.;Serum levels of hsCRP. Timepoint: Before and after the intervention. Method of measurement: ELIZA KIT.;Serum levels of TNF-a. Timepoint: Before and after the intervention. Method of measurement: ELIZA KIT.;Anthropometric indices. Timepoint: Before and after the intervention. Method of measurement: Scale, Stadiometer,Tape.;Body composition indices. Timepoint: Before and after the intervention. Method of measurement: Impedance bio-electric system.;Dietary intake. Timepoint: Before and after the intervention. Method of measurement: Three-day food recall questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood levels of fasting glucose. Timepoint: Before and after the intervention. Method of measurement: Enzymatic method.;Blood levels of fasting insulin. Timepoint: Before and after the intervention. Method of measurement: ELIZA KIT.;Serum levels of HbA1c. Timepoint: Before and after the intervention. Method of measurement: Spectrophotometry.;Blood levels of triglycerides. Timepoint: Before and after the intervention. Method of measurement: Enzymatic method.;Blood levels of total cholestrol. Timepoint: Before and after the intervention. Method of measurement: Enzymatic method.;Blood levels of HDL-cholesterol. Timepoint: Before and after the intervention. Method of measurement: Enzymatic method.;Blood levels of LDL-cholestrol. Timepoint: Before and after the intervention. Method of measurement: Friedewald formula. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBahram Pourghassem Gargari
Tabriz University of Medical Sciences
Outcome results
None listed