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Investigating the effectiveness of dextromethorphan on the sexual activity of women with sexual dysfunction

Investigating the effectiveness of dextromethorphan on the sexual activity of women with sexual dysfunction

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20100119003106N45
Enrollment
30
Registered
2024-03-06
Start date
2024-04-20
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female sexual dysfunction. Sexual dysfunction not due to a substance or known physiological condition

Interventions

Intervention group: 30 patients were randomly assigned to receive either 30mg dextromethorphan (Soft gelatin capsule dextromethorphan 15mg by Gelocough brand name producted by Dana company) or placebo

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Women aged 18-45 years Confirmed diagnosis of sexual dysfunction according to psychiatric diagnosis and FSFI questionnaire score under 26.55 Having a sexual partner for the last 6 months.

Exclusion criteria

Exclusion criteria: Lack of consent to continue participating in the study. Death of spouse or divorce. Pregnancy and breastfeeding during the study. The presence of severe communication disturbances (such as spousal violence) or other significant stressors that justify sexual problems. Spouse's sexual dysfunction. Menopause (natural or induced by surgery). Addictive disorders. Suffering from neurological and mental diseases such as depression disorders. Taking drugs that interfere with sexual function. Simultaneously suffering from other sexual disorders such as vaginismus, paraphilia and sexual identity disorder. Acute liver disease.

Design outcomes

Primary

MeasureTime frame
Changes in female sexual function score base on the female sexual function index (FSFI). Timepoint: before intervention, 4, 9 weeks after intervention. Method of measurement: Female Sexual Function Index (FSFI).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Fakharinia

Islamic Azad University

fakharinia.sara@gmail.com+98 21 2264 0051

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026