Evaluation the response rate in major depressive disorder after taking Sertraline as a predictive factor base on motor cortex magnetic brain stimulation.

Evaluation the response rate in major depressive disorder after taking sertraline as a predictive factor base on motor cortex magnetic brain stimulation.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20100119003106N44

Enrollment

Registered

2023-02-16

Start date

2022-05-22

Completion date

Unknown

Last updated

2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effect of sertraline in major depressive disorder. Major depressive disorder, single episode

Interventions

Intervention 1: Intervention group :48 patients with major depression in the age group of 18 to 65 years will be selected by a psychiatrist or by using the Hamilton and beck questionnaire and the amo

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: evaluation major depressive disorder Psychiatrist or Hamilton 24 question Age between 18-65 question provided by the Having informed satisfaction and motivation to cooperate and participate in completing the researcher No history of psychiatrist medication use in last two week

Exclusion criteria

Exclusion criteria: If a person has a specific acute neurological/ psychological disorder at the same time

Design outcomes

Primary

Measure	Time frame
Determining the Motor evoked potential of patients through transcranial magnetic stimulation. Timepoint: Before taking sertraline and 2 hours after taking sertraline. Method of measurement: Comparison of Motor evoked potential of patients before and after taking serteralin.	—

Secondary

Measure	Time frame
Hamilton and Beck depression questionnaire. Timepoint: Before taking sertraline and after taking sertraline. Method of measurement: Comparison of Hamilton and beck depression score of patients before and after taking serteralin.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmahsima moosavandi

Islamic Azad University

mahsimamoosavani1@gmail.com+98 21 2264 0599

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026