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The evaluation of the effect of adding Clonidine to Sertraline in the severity of attachment and suffering from detachment in depression of the post-breakup women.

The evaluation of the effect of adding Clonidine to Sertraline in the severity of attachment and suffering from detachment in depression of the post-breakup women.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20100105002999N10
Enrollment
90
Registered
2018-06-27
Start date
2018-02-20
Completion date
Unknown
Last updated
2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression. Major depressive disorder, single episode

Interventions

Intervention 1: Intervention group: Sertraline 50 milligram orally once daily plus 1/4 Clonidine 0.2 milligram Orally at night. Intervention 2: Control group: Sertraline 50 milligram Orally once dail

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Females aging 20-40 The experience of emotional breakup in the last 6 months informed consent(voluntary participation)

Exclusion criteria

Exclusion criteria: Comorbid anxiety disorder, Obsessive compulsive disorder Personality Disorder, Substance abuse, Psychosis, Bipolar Disorder Antihypertensive medication History of Heart disease Depression due to medical disorder Egodystonic attachment and dependency Severe depression with Beck score of 35 and above Essential turnovers after breakup e.g. divorce

Design outcomes

Primary

MeasureTime frame
Severity of attachment. Timepoint: measurement of the severity of attachment at the beginning and 8 weeks after intervention. Method of measurement: Visual analogue scale.;Suffering from detachment. Timepoint: measurement of the suffering from detachment at the beginning and 8 weeks after intervention. Method of measurement: Visual analogue scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzar Heidarzadeh

Tabriz University of Medical Sciences

a.heidarzadeh67@gmail.com+98 41 3380 3353

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026