The effect of two different tranquilizer drugs on anxiety in the patients candidate for surgery

The comparison of the effect of alprazolam and zaleplon on anxiety in the patients candidate for surgery

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20100102002963N33

Enrollment

Registered

2021-10-18

Start date

2021-10-12

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effect of drug on anxiety before induction of anesthesia.

Interventions

Intervention 1: Intervention group 1: Patients in this group are given oral alprazolam (0.5 mg) the night before surgery. Intervention 2: Intervention group 2: Patients in this group are given oral za

Eligibility

Sex/Gender

Female

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Female patients Candidate for abdominal surgery Referred to Kowsar ward of Shahid Sadoughi Hospital in Yazd

Exclusion criteria

Exclusion criteria: Existence of moderate to severe systemic disease patient history of using of sedative or tranquilizer drugs history of addiction to opioids or any sedative or psychotropic drugs disagreement for cooperation in this study

Design outcomes

Primary

Measure	Time frame
Anxiety score. Timepoint: Before administration of study drug and before induction of anesthesia. Method of measurement: Based on VAS(0-10).	—

Secondary

Measure	Time frame
Systolic blood pressure. Timepoint: Before administration of study drug and before induction of anesthesia. Method of measurement: Using monitoring device.;Diastolic blood pressure. Timepoint: Before administration of study drug and before induction of anesthesia. Method of measurement: Using monitoring device.;Mean arterial pressure. Timepoint: Before administration of study drug and before induction of anesthesia. Method of measurement: Using monitoring device.;Heart rate. Timepoint: Before administration of study drug and before induction of anesthesia. Method of measurement: Using monitoring device.	—

Measure

Time frame

Systolic blood pressure. Timepoint: Before administration of study drug and before induction of anesthesia. Method of measurement: Using monitoring device.;Diastolic blood pressure. Timepoint: Before administration of study drug and before induction of anesthesia. Method of measurement: Using monitoring device.;Mean arterial pressure. Timepoint: Before administration of study drug and before induction of anesthesia. Method of measurement: Using monitoring device.;Heart rate. Timepoint: Before administration of study drug and before induction of anesthesia. Method of measurement: Using monitoring device.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Shekoufeh Behdad

Yazd University of Medical Sciences

drbehdad@ssu.ac.ir+98 35 3823 1932

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026