Comparison of the effect of intravenous osmolol and intravenous lidocaine on hemodynamic variables during laryngoscopy and tracheal intubation and postoperative nausea and vomiting in patients undergoing abdominal surgery.
Conditions
Interventions
Intervention 1: Intervention group 1: In this group, 0.5 mg/kg of Esmolol, from Myungmoon pharmaceutical Co., Ltd is injected intravenously and once immediately before induction of general anesthesia
Sponsors
Azad Islamic University Of Yazd
Eligibility
Sex/Gender
Female
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: All female patients are candidates for gynecological abdominal surgery
Exclusion criteria
Exclusion criteria: Arterial hypertension Ischemic heart disease Heart failure Pulmonary disease Addiction Renal disease Liver disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in systolic blood pressure. Timepoint: Immediately before drug injection immediately before laryngoscopy immediately after endotracheal intubation immediately after skin incision. Method of measurement: Operating room monitoring with Blood pressure cuff connected to the monitor and recording information in a questionnaire.;Determining and comparing the incidence of bradycardia ( heart rate <50 ). Timepoint: Immediately after the operation in recovery room. Method of measurement: Monitoring in the recovery room with a blood pressure monitor connected to the monitor and recording information in a questionnaire.;Determining and comparing the incidence of vomiting and nausea. Timepoint: Immediately after the operation in recovery room. Method of measurement: Question from the patient and registration in the questionnaire.;Changes in diastolic blood pressure. Timepoint: Immediately before drug injection Immediately before laryngoscopy Immediately after endothracheal intubation Immediately after skin incision. Method of measurement: Operating room monitoring with Blood pressure cuff connected to the monitor and recording information in a questionnaire.;Changes in mean arterial blood pressure. Timepoint: Immediately before drug injection Immediately before laryngoscopy Immediately after intubation Immediately after skin incision. Method of measurement: Operating room monitoring with Blood pressure cuff connected to the monitor and recording infirmation in a questionnaire.;Changes in heart rates. Timepoint: Immediately before drug injection Immediately before laryngoscoy Immediately after endothracheal intubation Immediately after skin incision. Method of measurement: Operating room monitoring with Blood pressure cuff connected to the monitor and recording information in a questionnaire.;Determining and comparing the incidence of hypotension side effects ( systolic blood pressure <9 ) or drop of more than 20% of the base rate. Timepoint: Immediately after the operat | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Shekoufeh Behdad
Yazd University of Medical Sciences
Outcome results
None listed