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The effect of L-carnitine on improving heart function in hemodialysis patients

The effect of taking L-carnitine tablets on improving heart function in hemodialysis patients with heart failure, a double-blind clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20100102002954N27
Enrollment
92
Registered
2022-06-11
Start date
2022-06-22
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease with heart failure. Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease

Interventions

Intervention 1: Intervention group: After justifying the patients and providing the necessary training, routine treatment includes: use of oxygen, drugs that strengthen the contractile strength of the

Sponsors

Shahroud University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with definitive diagnosis of chronic kidney disease and need dialysis; Have a definite diagnosis of mild to moderate heart failure (EF <45); Age range 15- 65 years; History of continuous dialysis for at least the last six months; Stable vital signs; Have a controlled and consistent diet throughout the study;

Exclusion criteria

Exclusion criteria: Existence of digestive problems such as severe nausea and vomiting; Existence of severe and relatively severe coagulation problems; Existence of simultaneous chronic lung and liver disease; Taking any L-carnitine supplement in the past month; Non-participation in the study

Design outcomes

Primary

MeasureTime frame
Measuring of Ejection Fraction (EF). Timepoint: Once a Month. Method of measurement: Standard method of echocardiography.;Measurement of left ventricular diastolic end diameter (LVEDD). Timepoint: Once a Month. Method of measurement: Standard method of echocardiography.

Secondary

MeasureTime frame
Measurement of heart-to-chest diameter ratio (T/C). Timepoint: Once a Month. Method of measurement: Standard chest x-ray.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Reza Ghafarmanesh

Shahroud University of Medical Sciences

gigmedicine61@gmail.com+98 23 3234 2000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026