Chronic Asthma. Severe persistent asthma
Conditions
Interventions
Intervention 1: Intervention group: for patients in the intervention group, in addition to routine treatments involving the use of inhaled sprays (airway dilators and corticosteroids) , azithromycin 2
Sponsors
Shahroud University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with a diagnosis of chronic asthma by spirometric and clinical findings, Chronic asthma for at least the last six months, Do not take any antibiotics for at least the last month, Conscious consent to participate in research.
Exclusion criteria
Exclusion criteria: Incidence of any severe asthma attack during the study period, Hypersensitivity to azithromycin or intolerance during treatment, Existence of infectious and severe respiratory diseases in at least one month, History of any surgery on the respiratory tract, Existence of severe heart disease that has led to severe respiratory problems.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measuring the severity of chronic asthma. Timepoint: Once a month. Method of measurement: ACQ standard questionnaire.;Maximum expiratory volume per the first second (FEV1). Timepoint: Once a month. Method of measurement: Micromedical spirometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Measurement of expiratory nitric oxide ratio. Timepoint: Once a month. Method of measurement: Exhale nitric oxide test with Nobreath device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarnaz Adelnia
Shahroud University of Medical Sciences
Outcome results
None listed