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The effect of azythromycin in the control of refractory asthma patients

The effectiveness of azythromycin in the control of refractory asthma in patients with chronic asthma, a randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20100102002954N21
Enrollment
112
Registered
2020-10-03
Start date
2020-10-21
Completion date
Unknown
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe persistent asthma. Severe persistent asthma

Interventions

Intervention 1: Intervention group: for patients in the intervention group, in addition to routine treatments involving the use of inhaled sprays (airway dilators and corticosteroids) and oral prednis

Sponsors

Shahroud University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with a diagnosis of chronic asthma by spirometric and clinical findings, Existence of chronic asthma for at least the last six months, Do not take any antibiotics for at least the last one month, Conscious consent to participate in research.

Exclusion criteria

Exclusion criteria: Incidence of any asthma attack during the research period Allergy to azythromycin or intolerance during treatment Existence of infectious and severe respiratory diseases in at least one month

Design outcomes

Primary

MeasureTime frame
Measuring the severity of chronic asthma. Timepoint: Once a month. Method of measurement: ACQ standard questionnaire.;Maximum expiratory volume per second (FEV1). Timepoint: Once a month. Method of measurement: Micromedical spirometer.

Secondary

MeasureTime frame
Measurement of expiratory nitric oxide ratio. Timepoint: Once a month. Method of measurement: Exhale nitric oxide test with Nobreath device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfsane Nikravesh

Shahroud University of Medical Sciences

a_nikravesh@yahoo.com+98 23 3234 2000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026