Oral Lichen Planus. Lichen planus
Conditions
Interventions
Intervention 1: Intervention group: Consumption of 80 mg oral Curcumin capsule once a day for 1 month. Intervention 2: Control group: Consumption of 2 capsules of Prednizolone 5mg once a day for 1 mon
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with Oral lichen planus(confirmed by clinical examination, biopsy and histopathological evaluation)
Exclusion criteria
Exclusion criteria: Pregnancy Breastfeeding Patients who take corticosteroid Patients with increased hepatic enzyme and patients who take anti coagulation and anti platelet drug, like Warfarin. Orthodontic appliences Patients with Peptic ulcer, Gall-bladder stone Existance of any neoplasms or viral infections Receiving topical treatment for OLP during last 2 weeks or systemic treatment of OLP during last 4 weeks Consumption of Azathioprine, Cyclosporine, UVA,PUVA or UVB during last month The presence of allergies to Corticosteroids or herbal drugs like Curcumin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of pain. Timepoint: Before treatment and 1,2,4 week after treatment. Method of measurement: Use of Visual Analogue Scale(VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Size of the Lichen planus lesions. Timepoint: Before treatment and 1,2,4 week after treatment. Method of measurement: Tongprasom scale(0-5). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Seyed Javad Kia
Rasht University of Medical Sciences
Outcome results
None listed