A comparative study on the effect of fentanyl, morphine and methadone on hemodynamics of patients

A comparative study on the effect of fentanyl, morphine and methadone on hemodynamics of patients undergoing laryngoscopy and intubation in chronic users taking drugs by inhaler

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20100101002946N10

Enrollment

150

Registered

2018-10-28

Start date

2018-11-06

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tracheal intubation. Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

Interventions

Intervention 1: The first intervention group will receive intravenous 0.6 mg fentanyl. After 2 minutes oxygenation with 100% oxygen, patients undergo laryngoscopy with Macintosh curved blades 4 or 5 a

Eligibility

Sex/Gender

All

Age

No minimum to 65 Years

Inclusion criteria

Inclusion criteria: Patients taking drugs by inhaler Under 65 years old

Exclusion criteria

Exclusion criteria: History of heart disease History of high blood pressure, diabetes and other systemic diseases Patients who take drugs orally

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: Immediately and 5 minutes after laryngoscopy and intubation. Method of measurement: Using the pressure gauge.;Pulse. Timepoint: Immediately and 5 minutes after laryngoscopy and intubation. Method of measurement: Using Holter Monitoring.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Mosadegh

Kermanshah University of Medical Sciences

majidmosadegh4@gmail.com+98 83 3427 6309

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026