treatment resistant depression. Major depressive disorder, single episode, severe without psychotic features
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosis of the disorder based on DSM-V diagnostic criteria by a psychiatrist Obtaining written consent from the patient to participate in the study, Registration of demographic information Having a score of 14 to 28 HAM-D Minimum moderate depression Consumption of at least two courses Have received adequate doses of antidepressants for 8 weeks and have more than fourteen HAM-D.
Exclusion criteria
Exclusion criteria: Patients with history of psychotic episodes, severe physical illness, and suicidal or homicidal ideation will not be included in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression score on HAM-D. Timepoint: Before study, week 4 and week 8. Method of measurement: Hamilton Depression Rating Scale (HDRS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Mazandaran University of Medical Sciences