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Comparison of pain intensity and intrathecal complications of 50 and 100 µg morphine with very low dose of naloxone in patients undergoing cesarean section

Comparison of pain intensity and intrathecal complications of 50 and 100 µg morphine with very low dose of naloxone in patients undergoing cesarean section

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20091219002883N6
Enrollment
94
Registered
2021-10-21
Start date
2021-10-17
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

????? ??? ?? ????? ??????. Other chronic pain

Interventions

Intervention 1: 50 micrograms of intrathecal morphine with bupivacaine will be injected intravenously with 20 ng of naloxone after entering the operating room. Number of injections 1 time. Interventio

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Pregnant women with prior planning for cesarean section without Majo disease Absence of pregnancy-induced disease such as preeclampsia Term twin pregnancy (37 to 42 weeks) First or second pregnancy Tendency to cesarean delivery by spinal anesthesia

Exclusion criteria

Exclusion criteria: Dissatisfaction with participating in the study Any contraindications to anesthesia with spinal technique History of any idiocyncratic allergy or reaction to opioid drugs Chronic pain syndrome or regular use of opioids There is predictable evidence of anomaly in the fetus Allergy or intolerance to ketorolac, ibuprofen or oxycodone • Body mass index above 40 Failure of spinal anesthesia Prolongation of operation time

Design outcomes

Primary

MeasureTime frame
Reduce pain. Timepoint: The first 24 hours after cesarean section. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
The rate of nausea. Timepoint: Once every 6 hours for the first 24 hours after surgery. Method of measurement: questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammadreza Habibi

Mazandaran University of Medical Sciences

mohammadreza.habibi@gmail.com+98 11 3332 3023

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026