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Comparison of Ventolin nebulizer with supportive treatment in Transient tachypnea of the newborns (TTN) admitted to the neonatal intensive care unit (NICU) of Imam Khomeini and Bouali Sari hospitals of Sari

Comparison of Ventolin nebulizer with supportive treatment in Transient tachypnea of the newborns (TTN) admitted to the neonatal intensive care unit (NICU) of Imam Khomeini and Bouali Sari hospitals of Sari

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20091201002801N6
Enrollment
60
Registered
2023-07-23
Start date
2023-07-01
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Transient tachypnea of newborn. Transient tachypnea of newborn

Interventions

Intervention 1: Intervention group: In the intervention group, 0.1 mL of salbutamol (Ventolin, salbutamol sulfate 5 mg/mL) is nebulized in 3 mL of 0.9% normal saline. The standard dose of salbutamol i

Sponsors

Vice chancellor for research, Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 30 Days

Inclusion criteria

Inclusion criteria: Neonates with gestational age more than 34 weeks Tachypnea with or without cyanosis Respiratory distress Chest X-ray findings in favor of TTN

Exclusion criteria

Exclusion criteria: Meconium aspiration Other diseases in the radiography such as pneumonia and... Complex Coronary heart disease (CHD) Tachycardia above 180 Silverman Anderson score less than 46 Ventilator therapy since birth Diagnosis of RDS during hospitalization Administration of surfactant with diagnosis of RDS

Design outcomes

Primary

MeasureTime frame
Primary CPAP (continuous positive airway pressure) duration. Timepoint: Time interval from start to end of CPAP. Method of measurement: Minute and hour.;Oxigen therapy duration. Timepoint: Time interval from start to end of Oxigen therapy. Method of measurement: Minute and hour.;Hospitalization length. Timepoint: Time from hospitalization to discharge. Method of measurement: Day.;Time to start feeding based on Silverman Anderson score less than 4. Timepoint: Time to start feeding in day. Method of measurement: Calendar.;Stabilization of respiratory rate and heart rate. Timepoint: Calculate the stabilization time of respiratory rate and heart rate. Method of measurement: Hour.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaedeh Gouran

Mazandaran University of Medical Sciences

maedeh.gooran@gmail.com+98 11 3334 2334

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026