Benzodiazepine poisoning. Poisoning by, adverse effect of and underdosing of benzodiazepines
Conditions
Interventions
Intervention 1: Intervention group: Caffeine with a dose of 100 mg and once every 8 hours and flumazenil with a dose of 200 microns and once every hour along with 5% dextrose serum. Intervention 2: Co
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
14 Years to No maximum
Inclusion criteria
Inclusion criteria: Age above 14 years old Benzodiazepine poisoning has been confirmed through the urine toxicology screen of the patient Loss of consciousness GCS less than 13 No head trauma Do not have any contraindications to receiving flumazenil No accompanying poisoning
Exclusion criteria
Exclusion criteria: Age below 14 years Not having a positive urine screen for benzodiazepines No loss of consciousness GCS 14 15 Having head trauma Having a contraindication to receiving flumazenil Having accompanying poisoning Allergy to caffeine Having underlying metabolic disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of consciousness. Timepoint: Every 8 hours. Method of measurement: GCS. | — |
Secondary
| Measure | Time frame |
|---|---|
| The patient's time to wake up after receiving the first dose of caffeine. Timepoint: After administration of the first dose of caffeine and then every 24 hours. Method of measurement: hours and every 24 hours is considered a day. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBabak Mosftafa zade
Shahid Beheshti University of Medical Sciences
Outcome results
None listed