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Effect of symbiotic supplement on breast cancer recurrence

Effect of symbiotic supplement on serum adiponectin, hs-CRP, TNF-a, Apo A1 and Apo-B100 concentration in obese and overweight breast cancer survivors with low calorie diet

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20091114002709N49
Enrollment
76
Registered
2018-05-18
Start date
2018-05-30
Completion date
Unknown
Last updated
2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer. Malignant neoplasm of breast

Interventions

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
50 Years to 75 Years

Inclusion criteria

Inclusion criteria: Female breast cancer survivors (or Cessation of menstruation for at least 6 months prior to chemotherapy) Age range (50-75) BMI = 25 - 40 Kg/m2 At least one month has passed since the last radiotherapy Complete treatment of stage 1 - 4 breast cancer survivors Type of breast cancer : ER/PR+ and HER2- Willingness to cooperate and sign a written informed consent

Exclusion criteria

Exclusion criteria: History of Diabetes, acute heart failure, cirrhosis hepatic, acute and chronic renal failure History of autoimmune and infectious disease weight loss diet during the 6 months prior to study Smoking Alcohol consumption Nutrition supplement consumption

Design outcomes

Primary

MeasureTime frame
Adiponectin. Timepoint: Before intervention and 8 weeks after the start of intervention. Method of measurement: Elisa method.

Secondary

MeasureTime frame
Tumor Necrosis Factor alpha (TNF-a). Timepoint: Before intervention and 8 weeks after the start of intervention. Method of measurement: Elisa method.;High-sensitivity C-reactive protein (hs-CRP). Timepoint: Before intervention and 8 weeks after the start of intervention. Method of measurement: Elisa method.;Apolipoprotein-A1 (Apo-A1). Timepoint: Before intervention and 8 weeks after the start of intervention. Method of measurement: Elisa method.;Apolipoprotein-B100 (Apo-B100). Timepoint: Before intervention and 8 weeks after the start of intervention. Method of measurement: Elisa method.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahsa Raji Lahiji

Iran University of Medical Sciences

Rajimahsa@yahoo.com+98 21 4401 3375

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 24, 2026