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Effect of anti lophomonas parasite treatment on patients chronic cough well-being

Effect of anti lophomonas parasite treatment on patients chronic cough well-being

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20091111002695N10
Enrollment
60
Registered
2020-12-07
Start date
2020-12-05
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: chronic cough. Condition 2: Lophomonas Blattarum. Cough

Interventions

Intervention 1: Intervention group:Tinidazole 500mg in form of tablet, one each 12 hours, for14 days. The Active Pharmaceutical Ingredient is provided by Pars daru Pharmaceutical company. Intervention

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to No maximum

Inclusion criteria

Inclusion criteria: patients suffering from more than one months cough who could not be controlled by past medical treatments patients with normal physical examination patients with normal chest-x-ray

Exclusion criteria

Exclusion criteria: drug allergy proven asthma Tuberculosis(TB), gastroesophageal reflux(GERD) , ear wax, Chronic Obstructive Pulmonary disease(COPD), Carcinoma,hemoptesis Angiotensin converting enzyme inhibitors(ACEI) users

Design outcomes

Primary

MeasureTime frame
Lophomonas Blattarum being in smear or Bronchoalveolarlavage. Timepoint: Before intervention and 14 days after intervention. Method of measurement: Trichrome staining.;Chronic cough grading. Timepoint: Before intervention and 14 days after intervention. Method of measurement: Global Initiative for Asthma (GINA) guideline.

Secondary

MeasureTime frame
Dyspnea. Timepoint: Before intervention and 14days after intervention. Method of measurement: physical examination.;Sputum inflammatory cells. Timepoint: Before intervention and 14days after intervention. Method of measurement: sputum cytology.;Dyspnea garding. Timepoint: Before intervention and 14 days after intervention. Method of measurement: GINA(global strategy for asthma).;Body temperature. Timepoint: Before intervention and 14days after intervention. Method of measurement: Thermometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Mirsadraee

Islamic Azad University

majidmirsadraee@mshdiau.ac.ir+98 51 3870 4347

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026