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Comparison of the effectiveness of azithromycin capsules and zinc elemental capsules with azithromycin capsules alone in the treatment of acne vulgaris

Comparison of the effectiveness of azithromycin capsules and zinc elemental capsules with azithromycin capsules alone in the treatment of mild to moderate acne vulgaris

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20091012002581N12
Enrollment
60
Registered
2024-05-10
Start date
2024-03-20
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild to moderate acne vulgaris. Acne vulgaris

Interventions

Intervention 1: Intervention group: Group A azithromycin capsule 250 mg once a day for month. Intervention 2: Intervention group: Group B zinc elemental capsules 50 mg once a day for three months.

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
11 Years to 30 Years

Inclusion criteria

Inclusion criteria: Patients with mild to moderate acne aged 11-30 years Patients who have more than 20 inflammatory lesions (papules and pustules) on one side of the face and no more than three nodules or cysts on the same side of the face. Not having other skin diseases involving the face Having patient satisfaction Not having other systemic diseases aggravating acne, such as Cushing's syndrome, PCO, adrenal hyperplasia, acquired and innate immune deficiency, steroid acne and acneiform rashes, etc. Patients who have not used oral or topical anti-acne drugs in the last month, including natural and UV light and herbal and traditional acne treatments.

Exclusion criteria

Exclusion criteria: Patients who use topical or systemic steroids. Patients who use anti-androgen combinations. Patients who have used oral or topical anti-acne drugs even including natural light and UV in the last month. The presence of other facial skin dermatoses and other systemic diseases that aggravate acne, such as Cushing's syndrome, PCO, adrenal hyperplasia, acquired and innate immune deficiency, steroid acne and acneiform rashes, etc. Patient dissatisfaction The presence of more than three nodules or cysts on one side of the face Patients with excoriate acne Age below 11 years and above 30 years Having an inflammatory disease on the face other than acne, such as contact, allergic or seborrheic dermatitis, etc.

Design outcomes

Primary

MeasureTime frame
Severity. Timepoint: Every 30 days. Method of measurement: History and clinical examination.

Secondary

MeasureTime frame
Patient satisfaction. Timepoint: every 30 days. Method of measurement: Questionnare.;Total acne lesions. Timepoint: Every 30 days. Method of measurement: clinical examination.;Index of acne severity. Timepoint: every 30 days. Method of measurement: clinical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hamide Herizchi

Tabriz University of Medical Sciences

herizchih@tbzmed.ac.ir+98 41 1336 4160

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026