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Comparing the efficacy of 0.025% Fluocinolone acetonide with and without 5% caffeine in topical treatment of chronic plaque psoriasis

Efficacy of 5% caffeine plus 0.025% Fluocinolone acetonide versus 0.025% Fluocinolone acetonide alone for topical treatment of chronic plaque psoriasis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20091012002581N10
Enrollment
40
Registered
2023-10-28
Start date
2023-11-22
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic plaque psoriasis. Psoriasis

Interventions

Intervention 1: Intervention group 1: Patients will receive the prepared cream containing 5% caffeine along with fluocinolone acetonide 0.025%. The creams are distributed in divided doses at the begin

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
7 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patient age over 7 years No history of immunosuppression or iatrogenic Not using medication or treatment methods to treat psoriasis in the two weeks before the study No history of caffeine allergy Not pregnant or currently breastfeeding Consent to participate in the study

Exclusion criteria

Exclusion criteria: Pregnant or lactating women Aggravation of the disease during the study Joint involvement during the study that requires oral treatment Sensitization while using the drug during the study (such as vesicular rash, erythema, itching, etc.)

Design outcomes

Primary

MeasureTime frame
The rate of recovery of lesions. Timepoint: Patients will be evaluated at the beginning of the study and at weekly intervals for three consecutive weeks. Method of measurement: Psoriasis area and severity index.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hamideh Herizchi Ghadim

Tabriz University of Medical Sciences

dr.herizchi@yahoo.com+98 41 1540 6612

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026