Poor ovarian response. Female infertility of other origin
Conditions
Interventions
Intervention 1: Intervention group: exosomes will be injected in the ovarian tissue by transvaginal ultrasonographic guidance at the day of oocyte punctuer under anesthesia after three months, ovarian
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 42 Years
Inclusion criteria
Inclusion criteria: Abnormal ovarian reserve test Antral follicle count <5 At least one previous IVF cycle <3 oocyte was retrieved.
Exclusion criteria
Exclusion criteria: Ovarian insufficiency due to gonadal dysgenesia and abnormality of chromosoms Male infertility
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AMH. Timepoint: Three months after intervention. Method of measurement: Blood test.;FSH. Timepoint: Three months after intervention. Method of measurement: Blood test.;Number of oocyte. Timepoint: Three months after intervention. Method of measurement: Follicle counts in transvaginal sonogram. | — |
Secondary
| Measure | Time frame |
|---|---|
| Biochemical pregnancy. Timepoint: Two weeks after embryo transfer. Method of measurement: ?BhCG measurement.;Clinical pregnancy. Timepoint: Four weeks after embryo transfer. Method of measurement: Fetal heart activity in transvaginal sonogram. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Davari Tanha
Tehran University of Medical Sciences
Outcome results
None listed