Evaluation exosomes on niche

The effectiveness of injecting mesenchymal cell-derived exosomes into cesarean scar in women with repeat caesarean section at the time of laparoscopic cesarean niche repair.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20091012002576N36

Enrollment

Registered

2024-02-24

Start date

2024-03-20

Completion date

Unknown

Last updated

2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic repair of niche. Maternal care for scar from previous cesarean delivery

Interventions

Intervention 1: Intervention group: During laparoscopic repair cesarean scar will be resected then uterine incision will be repaired by vicryl 1and exosomes injected. Intervention 2: Control group: Du

Eligibility

Sex/Gender

Female

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients with niche and infertility Patients with niche and pelvic pain Patients with niche and AUB Patients with niche and recurrent implantation failure

Exclusion criteria

Exclusion criteria: Patients who are not candidate for laparoscopic surgery

Design outcomes

Primary

Measure	Time frame
Evaluation of niche by transvaginal sonogram. Timepoint: Six weeks after surgery. Method of measurement: Transvaginal sonogram.;AUB, pelvic pain. Timepoint: Sixth weeks after surgery. Method of measurement: Patient History.;Infertility. Timepoint: Two months after surgery. Method of measurement: BhCG blood test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Davari Tanha

Tehran University of Medical Sciences

Fatedavtanha@gmail.com+98 21 8880 0115

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026