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Effect of Gh on pregnancy outcome in RIF

Evaluation the effect of growth hormone (Gh) on pregnancy outcome of recurrent implantation failure (RIF) via intrauterine infusion.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20091012002576N34
Enrollment
60
Registered
2023-10-06
Start date
2023-10-12
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility of other origin

Interventions

Intervention 1: Intervention group: for thirthy patients, intracavitary growth hormone will be injected by IUI ?(Intrauterine Insemination) catheter one cm above internal OS cervix, 0.5 cc of Gh(Cinat

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: History of recurrent implantation failure due to unknown etiology Having good quality mbryo

Exclusion criteria

Exclusion criteria: User of corticosteroids User of glucose control agents CNS tumors Uterine malformations Asherman syndrome Cavity distorting lesions Severe endometriosis Liver disease Severe male infertility Body mass index(BMI)>30 Uncontrolled hypothyroidism

Design outcomes

Primary

MeasureTime frame
Biochemical pregnancy. Timepoint: Two weeks after embryo transfer. Method of measurement: Beta HCG titer test (blood test).

Secondary

MeasureTime frame
Clinical pregnancy. Timepoint: Four weeks after embryo transfer. Method of measurement: Heart beat activity by transvaginal sonogram.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Davari Tanha

Tehran University of Medical Sciences

Fatedavtanha@gmail.com+98 21 8880 0115

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026