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Effect of prophylactic intravenous tranexamic acid on blood loss after cesarean delivery

Effect of prophylactic intravenous tranexamic acid on blood loss after cesarean delivery

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20091010002558N7
Enrollment
44
Registered
2020-12-08
Start date
2016-03-21
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postpartum blood loss.

Interventions

Intervention 1: Intervention group: Women in the study group, received one gram intravenous TA, 10 min before skin incision in 200 mL normal saline over 10 min. In this study, TA was supplied in 2 × 5

Sponsors

Ghoum University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria included age 18-35 years, single pregnancy, cesarean delivery, blood pressure less than 140 over 90, no history of thromboembolism and coagulation disease, no uterine myoma, no IUFD fetus, no decolonization and no history or Active heart, liver and kidney diseases

Exclusion criteria

Exclusion criteria: During cesarean section, if placental adhesions such as placenta, increta and percorta are observed, individuals will be excluded.

Design outcomes

Primary

MeasureTime frame
Blood loss after cesarean. Timepoint: The lost blood will be controlled in two times: A: The time of placenta departure until the end of cesarean section B: From the end of cesarean section to 2 hours after delivery. Method of measurement: In practice, the volume of blood in the suction and the weight of the gases and blood-stained tampons will be used to check for postpartum hemorrhage. A digital scale (with an error rate of 10 grams) will be used to weigh gases and guns. To collect the blood lost after the cesarean section, immediately after the end of the cesarean section, a disposable plastic cover with a certain weight is spread under the cesarean section woman and she will be weighed 2 hours after the cesarean section.;Hemoglobin and hematocrit levels. Timepoint: Hemoglobin and hematocrit levels will be monitored before and 12-24 hours after delivery. Method of measurement: hemoglobin and hematocrit are measured by blood test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEsmat Jafarbegloo

Ghoum University of Medical Sciences

jafarbegloo_2004@yahoo.com+98 25 3783 1371

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026