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Anesthetic efficacy of Dexamethasone added to Lidocaine for inferior alveolar nerve block in patients with symptomatic irreversible pulpitis

Anesthetic efficacy of Dexamethasone added to Lidocaine for inferior alveolar nerve block in patients with symptomatic irreversible pulpitis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20091004002541N7
Enrollment
100
Registered
2018-05-17
Start date
2016-08-01
Completion date
Unknown
Last updated
2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irreversible pulpitis. Pulpitis

Interventions

Intervention 1: Intervention group: 2 cartridges of 1.8 mL of 2% lidocaine with epinephrine each combined with 0.2 ml dexamethasone applied by using conventional inferior alveolar nerve block injectio

Sponsors

Vice chancellor for research, Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Eighteen years of age and over Being in good health condition Having a mandibular molar tooth with symptomatic irreversible pulpitis Normal periapical radiographic appearance (except for a widened periodontal ligament) Not having severe periodontal problem No history of allergy to local anesthesia or sulfite

Exclusion criteria

Exclusion criteria: Pregnancy or lactation Taking any medications that might cause altered pain sensation ?Any swelling or sinus tract near the target tooth Active sites of pathosis in the area of injection Inability of the patient to give an informed consent Lack of lip numbness within 15 minutes after injection

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Before treatment and after initiating root canal therapy. Method of measurement: Heft-Parker visual analog scale (VAS).

Secondary

MeasureTime frame
Post pain. Timepoint: During procedure. Method of measurement: Heft-Parker visual analog scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoud Saatchi

Esfahan University of Medical Sciences

saatchi@dnt.mui.ac.ir+98 31 3792 2822

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026