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The effects of magnesium and vitamin D supplement on muscle strength, muscle function, and inflammatory markers in middle-aged women.

The effects of magnesium and vitamin D supplement on muscle strength, muscle function, and inflammatory markers in middle-aged women.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20090822002365N20
Enrollment
90
Registered
2018-03-10
Start date
2018-04-04
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcopenia, muscle weakness, decrease of muscle strength. Muscle wasting and atrophy ,not elsewhere classified

Interventions

Intervention 1: Intervention group: Daily intake of one magnesium supplement (250 mg) and weekly intake of vitamin D (50000 IU) for 8 weeks (2 months). Intervention 2: Control group: Daily intake of

Sponsors

personal (expenses will payed by student)
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to 55 Years

Inclusion criteria

Inclusion criteria: Voluntary participation Age from 40 to 55 years old BMI>=25kg/m2 Having serum vitamin D less than 30 ng/ml

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Improvement of muscle strength in hand and foot. Timepoint: Before the intervention and two months later of intervention. Method of measurement: Dynamometer, Handgrip.

Secondary

MeasureTime frame
Hs-CRP. Timepoint: Before the intervention and two months later of intervention. Method of measurement: immunoturbidimetry.;TNF-a. Timepoint: Before the intervention and two months later of intervention. Method of measurement: Concentration of TNF-a in serum using ELISA kit.;IL-6. Timepoint: Before the intervention and two months later of intervention. Method of measurement: Concentration of IL-6 in serum using ELISA kit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Reza Vafa

Iran University of Medical science

vafa.m@iums.ac.ir+98 21 8670 4734

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026