Oral sucrose 24% for reducing pain in preterm neonates

Comparison of single to divided-doses of oral sucrose 24% to reduce pain in preterm neonates

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20090813002342N13

Enrollment

120

Registered

2021-03-11

Start date

2020-07-10

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute pain in heal lancing. Acute pain

Interventions

Intervention 1: Intervention group: Preterm infants in this group receive 24% sucrose solution as a single dose before blood samples are taken from the heel. The dose of sucrose is 0.5 ml/kg, which is

Eligibility

Sex/Gender

All

Age

1 Days to 28 Days

Inclusion criteria

Inclusion criteria: All preterm infants undergoing heel lance.

Exclusion criteria

Exclusion criteria: Infants weighing less than 800 grams. Infants who do not receive oral intake. Infants with unstable hemodynamic status. Infants receiving antiepileptic, opioid, or sedative medications. Babies under mechanical ventilation or NCPAP. Infants with decreased level of consciousness. Infants with multiple congenital anomalies and abnormal facial structures that make it difficult to interpret the pain criteria.

Design outcomes

Primary

Measure	Time frame
Pain intensity using the Premature infant pain profile-R scoring tool. Timepoint: 30 seconds after heel lance. Method of measurement: Calculation of indicators in PIPP-R.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohamadreza rafati

Mazandaran University of Medical Sciences

mrrafati@mazums.ac.ir+98 11 3354 3084

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026