Effect of dexmedetomedine and fentanyl in venous catheter placement

Comparison of efficacy and safety between dexmedetomedine and fentanyl for central venous catheter placement in pediatric intensive care unit (PICU)

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20090813002342N10

Enrollment

Registered

2020-09-05

Start date

2020-07-07

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sedation in children for placement of a central venous catheter. Encounter for adjustment and management of vascular access device

Interventions

Intervention 1: Intervention group: Children receiving dexmedetomidine for placement of central venous catheter. Patients in this group receive dexmedetomidine intravenously at a dose of 1 mcg/kg for

Eligibility

Sex/Gender

All

Age

1 Months to 18 Years

Inclusion criteria

Inclusion criteria: Children one month to 18 years old who need a central venous catheter placement enter to study

Exclusion criteria

Exclusion criteria: bradycardia hypertension above 99% apnea before the study cardiac conduction impairment in the ECG before drug administration patients with ASA physical status classification IV renal failure known heart failure history of heart surgery shock

Design outcomes

Primary

Measure	Time frame
Adequate sedation following the use of dexmedetomedine or fentanyl for central venous catheter placement. Timepoint: Before and at the end of the administration of the drug loading dose and then every 5 minutes until the end of catheter placement. Method of measurement: Ramsay Sedation Scale.	—

Secondary

Measure	Time frame
Blood pressure. Timepoint: Before and at the end of drug loading dose, then every 5 minutes until the end of catheter placement. Method of measurement: By digital monitoring device in PICU.;Heart rate. Timepoint: Before and at the end of drug loading dose, then every 5 minutes until the end of catheter placement. Method of measurement: By digital monitoring device in PICU.;Respiratory rate. Timepoint: Before and at the end of drug loading dose, then every 5 minutes until the end of catheter placement. Method of measurement: By digital monitoring device in PICU.;O2 saturation. Timepoint: Before and at the end of drug loading dose, then every 5 minutes until the end of catheter placement. Method of measurement: By digital monitoring device in PICU.	—

Measure

Time frame

Blood pressure. Timepoint: Before and at the end of drug loading dose, then every 5 minutes until the end of catheter placement. Method of measurement: By digital monitoring device in PICU.;Heart rate. Timepoint: Before and at the end of drug loading dose, then every 5 minutes until the end of catheter placement. Method of measurement: By digital monitoring device in PICU.;Respiratory rate. Timepoint: Before and at the end of drug loading dose, then every 5 minutes until the end of catheter placement. Method of measurement: By digital monitoring device in PICU.;O2 saturation. Timepoint: Before and at the end of drug loading dose, then every 5 minutes until the end of catheter placement. Method of measurement: By digital monitoring device in PICU.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohamadreza rafati

Mazandaran University of Medical Sciences

mrrafati@mazums.ac.ir+98 15 1223 3014

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026