Evaluation of the effect of enoxaparin in preventing blood clot formation in Intensive care unit patients following physical trauma

The effect of enoxaparin on coagulation factors in venous thromboembolism prophylaxis in patients admitted to the Intensive care unit after trauma

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20090808002310N4

Enrollment

Registered

2025-05-03

Start date

2019-01-19

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trauma. Acute pain due to trauma

Interventions

Intervention Group: Initially, trauma patients will be assessed for the feasibility of initiating enoxaparin treatment within the first 24 hours following trauma. If there are no contraindications, en

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are admitted to the ICU of Shahid Rajaee Hospital in Shiraz following trauma and it is possible to start enoxaparin within the first 24 hours after trauma.

Exclusion criteria

Exclusion criteria: Chronic renal failure Previous allergy to enoxaparin Pregnant women History of thromboembolism Use of anticoagulant medications Use of oral contraceptive pills (OCP) History of coagulation disorders BMI over 30

Design outcomes

Primary

Measure	Time frame
Anti-factor Xa Assay. Timepoint: 4 hours after the first dose injection. Method of measurement: blood sample test of the patient.;APACHI II. Timepoint: The first 24 hours of the patient's admission to the ICU. Method of measurement: based on 17 standard parameters.;Injury Severity score. Timepoint: length of stay in the ICU. Method of measurement: "according to the standard formula.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Aalinezhad

Shiraz University of Medical Sciences

fateme.aalinezhad@yahoo.com0987136281460

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026