Evaluation of the effect of herbal anti-asthma product along with standard treatment on the intervals and severity of moderate chronic asthma attacks in children and adolescents 6 to 18 years

Clinical study of the effect of oral products of three plants: licorice (Glycyrrhiza glabra), fragrant violet (Viola adorata) and tarpaulin (Operculina turpethum) as an add-on on the intervals and severity of moderate chronic asthma attacks in children and adolescents 6 to 18 years

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20090808002306N6

Enrollment

Registered

2021-01-29

Start date

2020-12-21

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

moderate persistent asthma. Moderate persistent asthma

Interventions

Intervention 1: Intervention group: In this study, subjects in the case group received 4 packs of 30 anti-asthma pills (containing components: asparagine, hydroxycinnamic acids, glycyrrhizin, salicyli

Eligibility

Sex/Gender

All

Age

6 Years to 18 Years

Inclusion criteria

Inclusion criteria: All patients between 6 and 18 years old with chronic asthma in children and adolescents with moderate severity according to the Nelson Pediatrics textbook published in 2018 (page 202) Do not use other drugs at the same time and outside the official treatment protocol that is effective on the disease. No possible history of underlying cardiovascular, renal, hepatic and biliary tract diseases

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Spiro metric Respiratory Test Index (FEV1). Timepoint: Spirometry tests are taken from patients before the start of the study and the test is performed again one month after taking the drug. Method of measurement: Pulmonary indices are recorded by spirometry.;Spiro metric Respiratory Test Index (FVC). Timepoint: Spirometry tests are taken from patients before the start of the study and the test is performed again one month after taking the drug. Method of measurement: Pulmonary indices are recorded by spirometry.;Spiro metric Respiratory Test Index (FEV1/FVC). Timepoint: Spirometry tests are taken from patients before the start of the study and the test is performed again one month after taking the drug. Method of measurement: Pulmonary indices are recorded by spirometry.;Number of cough attacks per day or week. Timepoint: Before the study and one month after taking the drug. Method of measurement: By asking parents and registering on the data collection form.;Number of puffs used salbutamol spray per day. Timepoint: Before the study and one month after taking the drug. Method of measurement: By asking parents and registering on the data collection form.;Severe restrictions on exercise or activity. Timepoint: Before the study and one month after taking the drug. Method of measurement: By asking parents and registering on the data collection form.;Evaluation of quality of life and asthma control in children and adolescents. Timepoint: Before the study and one month after taking the drug. Method of measurement: Using two asthma control questionnaires completed by parents and children or adolescents.;Number of shortness of breath per day or week. Timepoint: Before the study and one month after taking the drug. Method of measurement: By asking parents and registering on the data collection form.	—

Measure

Time frame

Spiro metric Respiratory Test Index (FEV1). Timepoint: Spirometry tests are taken from patients before the start of the study and the test is performed again one month after taking the drug. Method of measurement: Pulmonary indices are recorded by spirometry.;Spiro metric Respiratory Test Index (FVC). Timepoint: Spirometry tests are taken from patients before the start of the study and the test is performed again one month after taking the drug. Method of measurement: Pulmonary indices are recorded by spirometry.;Spiro metric Respiratory Test Index (FEV1/FVC). Timepoint: Spirometry tests are taken from patients before the start of the study and the test is performed again one month after taking the drug. Method of measurement: Pulmonary indices are recorded by spirometry.;Number of cough attacks per day or week. Timepoint: Before the study and one month after taking the drug. Method of measurement: By asking parents and registering on the data collection form.;Number of puffs used salbutamol spray per day. Timepoint: Before the study and one month after taking the drug. Method of measurement: By asking parents and registering on the data collection form.;Severe restrictions on exercise or activity. Timepoint: Before the study and one month after taking the drug. Method of measurement: By asking parents and registering on the data collection form.;Evaluation of quality of life and asthma control in children and adolescents. Timepoint: Before the study and one month after taking the drug. Method of measurement: Using two asthma control questionnaires completed by parents and children or adolescents.;Number of shortness of breath per day or week. Timepoint: Before the study and one month after taking the drug. Method of measurement: By asking parents and registering on the data collection form.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Mohammad Sabzghabaee

Esfahan University of Medical Sciences

sabzghaba@pharm.mui.ac.ir+98 31 3792 7070

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026