?Acute cutaneous leishmaniasis. Cutaneous leishmaniasis
Conditions
Interventions
Intervention 1: Intervention group: Applies the 50% weight/weight Pistacia atlantica oleoresin cream to the lesion every 12 hours for 8 weeks. Intervention 2: Control group: Applies the cream lacking
Sponsors
Iranian academic center for education culture and research
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
5 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients whose cutaneous leishmaniasis diagnosis has been confirmed by test Patients whose lesions size is less than 3 centimeters Patients who have 2 symmetrical lesions Patients whose lesions are not on cartilage or joint Patients whose lesions are not on the face Patients whose lesions are not in sight Patients who do not need to receive Glucantime (antimoniate)
Exclusion criteria
Exclusion criteria: Women who are in the childbearing age Women who breastfeed Patients who have sporotrichoid or satellite lesions Patients who have used immunosuppresive drugs during the past 6 months Patients who have received topical or systemic antileishmanial drugs during the past 1 month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lesion area. Timepoint: Measurement of the lesion area before intervention and 2, 4, 8 and 12 weeks after intervention. Method of measurement: Graph paper.;Percentage of patients who have amastigotes in the lesion. Timepoint: Evaluation of the presence of amastigotes in the lesion before intervention and 4, 8 and 12 weeks after intervention. Method of measurement: Direct smear method. | — |
Secondary
| Measure | Time frame |
|---|---|
| Complete blood count. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Auto-analyzer.;Serum glutamic pyruvic transaminase. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Autoanalyzer.;Serum glutamic oxaloacetic transaminase. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Autoanalyzer.;Blood creatinine. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Autoanalyzer.;Blood urea nitrogen. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Autoanalyzer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Saeed Kianbakht
Iranian academic center for education culture and research
Outcome results
None listed