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Efficacy of Bupropion on sexual function of women with orgasmic disorder

Efficacy of Bupropion on sexual function of women with orgasmic disorder

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20090801002266N9
Enrollment
30
Registered
2018-12-07
Start date
2018-12-22
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orgasmic disorder. Female orgasmic disorder

Interventions

Intervention 1: Intervention group: Bupropion is given at a daily dose of 75 mg (half a tablet of 150 mg) per day, and the treatment is continued according to the effect of the symptoms on a weekly ba

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Reading and writing literacy Woman aged 18 to 50 years Negative pregnancy test and no action for pregnancy during the intervention Having a sexual partner (husband) who has no sexual dysfunction (spouse sexual intercourse is rejected by clinical interview). She is in a marital relationship for at least six months, not considering divorce or separation, and alternately having sex with her husband. The lack of active psychiatric illness Not having sexual desire and pain disorder (disparonius and vaginismus) simultaneously Non-menopause (natural or surgical) Not having a history of primary and secondary infertility The complaint of a global female orgasmic disorder should be as follows: a) Frequency of orgasms during sexual intercourse in less than 50% of sexual relationships. b) There is a disorder for at least 6 months. c) Has reached orgasm at least 3 times in the last 6 months. Not having anxiety disorder at the same time (Beck anxiety disorder score less than 10). Not having depressive disorder at the same time (Beck Depression Questionnaire score is less than 10). Not having sexual and paraphilia disorders History of seizure or head injury No substance abuse or alcohol abuse over the past year Non-use of psychiatric drugs and any drugs that affect sexual function (chronic use of opioids beta blockers, alpha-adrenergic drugs, psychotropic drugs) Failure to receive synchronous psychological intervention

Exclusion criteria

Exclusion criteria: Dissatisfaction to continue participating in the study at any time Pregnancy during the study Couple's death or divorce during the study

Design outcomes

Primary

MeasureTime frame
Changes in female sexual function score base on the female sexual function index. Timepoint: Before intervention 2, 4, 6, 8 weeks after intervention. Method of measurement: Female sex function index questionnaire.;Changes in female sexual satisfaction. Timepoint: Before intervention 2, 4, 6, 8 weeks after intervention. Method of measurement: Larsson Women's Sexual Satisfaction Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Gholam Reza Kheirabadi

Esfahan University of Medical Sciences

kheirabad@bsrc.mui.ac.ir+98 31 1222 2135

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026