Detoxification in regular and daily users of opium or heroin orally, injected or smoked. Opioid dependence with withdrawal
Conditions
Interventions
Intervention 1: Intervention group: With the onset of withdrawal symptoms, we begin treatment with 0.1 mg of clonidine. Then 2 to 4 mg of sublingual buprenorphine is prescribed (2 mg for amounts less
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Consent to participate in the study Having DSM-5 criteria for drug dependence Regular and daily consumption of opium or heroin orally, injected or smoked Not using other substances Age 20 to 60 years Absence of major psychiatric disorders and absence of physical illness, which is a ban on withdrawing drugs Not taking psychiatric drugs or any drugs that affects the central nervous system
Exclusion criteria
Exclusion criteria: The patient's unwillingness to continue cooperation Occurrence of any medical or ethical conflict with the patient's continued participation in the research Occurrence of physical and mental problems requires special interventions in the process of withdrawing drugs Returning to substance abuse in the treatment process
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Instant craving score in the Desires for Drug Questionnaire. Timepoint: The patient will be visited once a week for the first 2 weeks and once every two weeks for several months. After that, the visits are reduced to once a month. At each visit, the patient is examined by a physician. Method of measurement: Desires for Drug Questionnaire.;Reduction of cases of withdrawal from treatment. Timepoint: In both groups, data related to cases of non-referral and non-follow-up treatment will be recorded and compared at the end of the intervention and follow-up period. Method of measurement: Registration in the patient follow-up checklist.;The level of satisfaction with the detoxification process and the one-year follow-up period. Timepoint: The end of the detoxification period and the end of the one-year follow-up period. Method of measurement: at the end of detoxification period and at the end of one-year follow-up period) in the form of two questions in the text of the questionnaire and using It is measured by the Likert scoring scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Gholamreza Kheirabadi
Esfahan University of Medical Sciences
Outcome results
None listed